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Hydrogen Peroxide Teeth Whitening is a process that has been used for decades even though the first article on the topic was published in 1989. Most dentists use hydrogen peroxide teeth whitening in their office treatments. The hydrogen peroxide teeth whitening method is completely safe and effective for using at home. Side effects do occur with the hydrogen peroxide teeth whitening treatments such as tooth sensitivity to hot and cold whether done by a dentist or at home. Less frequently occurring side effects from hydrogen peroxide teeth whitening are sore throat, pain in the teeth, tingling of the tissues and headaches. Sometimes the side effects from the hydrogen peroxide teeth whitening treatments are severe enough to cause discontinuation of the procedure, but this is extremely rare.